The cast list on From Up on Poppy Hill includes:
- Gillian Anderson (X-Files)
- Sarah Bolger (The Tudors)
- Beau Bridges (Stargate)
- Jamie Lee Curtis (Halloween)
- Bruce Dern (Silent Running)
- Jeff Dunham
- Isabelle Furnham
- Christina Hendricks (Mad Men)
- Chris Noth (Law & Order, Sex in the City)
- Ron Howard (Happy Days)
- Emily Osment (Hannah Montana)
- Aubrey Plaza (Scott Pilgrim, Parks and Recreation)
- Chalie Saxton
- Alex Wolff
- Anton Yelchin (Star Trek)
